Abstract In the regional innovation system, the innovation subjects,including businesses, universities, insti-tutes, the government and the intermediate agencies with different functions and advantages, play a very im-portant role in improving and developing the regional innovation system. As a network whose data are open,this system involves the interaction between innovation subjects, the coordination between system, policy and environment, and the concerted action of all innovation factors. In this paper, we discuss the correlation mechanism between innovation subjects and the regional innovation system, finding that universities, institutes and businesses via data sharing and labor division, and intermediate agencies and local governments via their bridging, linking and supporting role can effectively realize their strategic aim of building the regional innovation system.
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