Abstract:The safety of medical staff and the prevention of cross-infection are very important in the special period. In order to prevent infectious diseases effectively during the epidemic period of COVID-19, according to different exposure levels, protective measures taken by medical staff are particularly crucial. ECG doctors perform their duties, but they must also pay attention to medical protection and prevention of crossinfection. Correct selection and application of disinfectants are also very important for ECG doctors. In this paper, protection during electrocardiogram examination, sterilization of ECG examination room and instrument disposal of disposable protective equipment and masks,classification and use of disinfectants are introduced. We hope it will be helpful in the prevention of COVID-19 infection.