Abstract：Although coronary intervention therapy has significantly reduced the shortterm mortality of patients with acute myocardial infarction, ventricular remodeling still occurs in about 30% of those patients after regular use of secondary prevention drugs for coronary heart disease. It directly leads to the progressive deterioration of systolic and diastolic function in the left ventricle, and newonset heart failure, resulting in increased mortality. Various factors such as myocardial infarct size, coronary intervention time window, coronary microcirculation reperfusion injury, and cellular molecules may participate in or affect this complex pathological process, but the unknown causes and risk factors still require to be explored further. It can provide references for taking appropriate clinical intervention measures so as to prevent ventricular remodeling after myocardial infarction, and reduce the incidence rate and mortality of heart failure. This paper reviews on the pathological development, influencing factors and corresponding intervention means of ventricular remodeling after myocardial infarction.
2019, Vol. 28 
