Abstract:In order to accurately describe hemodynamics of heart valve and its application in the cardiovascular system, this paper modeled the heart valve as a variable resistor and a current source in parallel and then a constant inductance in series according to electricliquid analogy. The governing equations of the left ventricular circulation were derived. The heart valve model divided the flow into two branches: flow through valve orifice and flow displaced by valve leaflets. The resistance depends on leaflet position and the heart valve closing motion was controlled with specified closing volume. For the mitral valve, Matlab was used to solve these equations to obtain circulation hemodynamics, which reflected the closing and leaking characteristics of the heart valve. The closing and leakage volumes were 3.30 mL and 2.30 mL, respectively, at stroke volume 63.60 mL or the normal cardiac output 4.58 L/min. The closing and leakage volumes were 14.70 mL and 25.40 mL, respectively, at the mitral regurgitation. This model can be used to simulate hemodynamics of the normal and regurgitated heart valve and thus arterial hemodynamics.
贺照明,刘艳芳,荆腾,张桂杰,刘洪艳,王颢. 可控关闭体积心脏瓣膜模型[J]. 排灌机械工程学报, 2019, 37(1): 1-6.
HE Zhaoming, LIU Yanfang, JING Teng, ZHANG Guijie, LIU Hongyan, WANG Hao. Heart valve model with controllable closing volume. Journal of Drainage and Irrigation Machinery Engin, 2019, 37(1): 1-6.